Research Articles
H3K27me3 ChIP-seq: A Comprehensive Guide from Polycomb Biology to Clinical Translation
This article provides a comprehensive resource for researchers and drug development professionals utilizing H3K27me3 ChIP-seq to study Polycomb-mediated repression.
Optimized ChIP-seq for Histone Modifications: A Complete Guide from Foundational Principles to Advanced Applications
This article provides a comprehensive guide for researchers and drug development professionals on optimizing Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) for histone modification analysis.
A Comprehensive Guide to Histone Mark Enrichment Analysis from ChIP-seq Data: From Foundational Concepts to Advanced Applications
This article provides a comprehensive guide for researchers and drug development professionals on histone mark enrichment analysis using ChIP-seq technology.
Mastering ChIP-seq: A Comprehensive Guide to H3K4me3, H3K27me3, and H3K9me3 Epigenetic Analysis
ChIP-seq is a cornerstone technique for profiling histone modifications like H3K4me3, H3K27me3, and H3K9me3, which play pivotal roles in gene regulation, cellular identity, and disease.
ChIP-Seq and Beyond: Decoding Histone Modifications in Gene Regulation, Disease, and Drug Discovery
This article provides a comprehensive resource for researchers exploring the epigenetic landscape through histone modifications.
Decoding Histone Modifications: A Comprehensive Guide to ChIP-Seq Peak Analysis and Interpretation
This article provides a comprehensive guide for researchers and drug development professionals on analyzing and interpreting ChIP-seq data for histone modifications.
Histone Modification ChIP-seq Analysis: A Comprehensive Guide from Fundamentals to Clinical Applications
This article provides a comprehensive guide to histone modification ChIP-seq analysis, covering fundamental principles, methodological workflows, troubleshooting strategies, and advanced validation techniques.
A Comprehensive Guide to Histone ChIP-seq: From Foundational Principles to Advanced Applications in Biomedical Research
This article provides a definitive, step-by-step guide to Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) for mapping histone modifications.
Validating STAR-Fusion Accuracy: A Comprehensive Guide for Cancer Researchers and Clinicians
This article provides a comprehensive framework for validating the accuracy of STAR-Fusion in detecting chimeric transcripts, a critical task in cancer genomics and drug development.
STAR RNA-seq Workflow: A Comprehensive Benchmarking and Optimization Guide for Biomedical Research
This article provides a definitive guide to the STAR RNA-seq alignment workflow, offering a critical comparison with alternative pipelines like Salmon and HISAT2.